<sup>1</sup>O<sub>2</sub> and Base Assisted Oxidative Conversion of β-Enaminoesters to α-Acyloxy-β-ketoesters under Visible Light Irradiation
Singlet oxygen (<sup>1</sup>O<sub>2</sub>) and base assisted conversion of β<i>-</i>enaminoesters to α-acyloxy-β-ketoesters is demonstrated under visible light irradiation. The reaction involves formation of an imine intermediate via ene-type pathway initiated by <sup>1</sup>O<sub>2</sub> followed by base promoted dimerization and hydrolysis steps. The method is mild, environmentally friendly, requires air as the oxidant, and gives the products in moderate to high yields.
Authors
- Nidhi Jain (ORCID: https://orcid.org/0000-0001-8645-430X)
- Rohit Kumar (ORCID: https://orcid.org/0000-0002-0809-8626)
- Deepak
Institutions
- Indian Institute of Technology Delhi (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1021/acs.joc.4c01994
- Citations
- 2
- Primary Topic
- Synthesis and Characterization of Pyrroles
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- Council of Scientific and Industrial Research, India
- Science and Engineering Research Board