Cytidine deaminase enhances liver cancer invasion by modulating epithelial-mesenchymal transition via NFκB signaling
We isolated highly metastatic cells and identified potential HCC metastasis-related genes. CDA promotes cell invasion by regulating EMT through the NF-κB pathway. Future studies are warranted to explore the potential of CDA as a biomarker for prognosis and therapeutic decision-making.
Authors
- Yi-Wen Wang (ORCID: https://orcid.org/0000-0002-4509-9572)
- Chau‐Ting Yeh (ORCID: https://orcid.org/0000-0001-7376-275X)
- Huei‐Tzu Chien (ORCID: https://orcid.org/0000-0002-4120-7070)
- Kwang‐Huei Lin (ORCID: https://orcid.org/0000-0002-5649-2222)
- Yang-Hsiang Lin (ORCID: https://orcid.org/0000-0003-4295-6062)
- Tzu-Kang Lin
- Chia‐Jung Liao
Institutions
- Fu Jen Catholic University (TW)
- Chang Gung University of Science and Technology (TW)
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- Biomedical Journal
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.bj.2024.100789
- Citations
- 2
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Chang Gung Memorial Hospital