Landscape of epithelial cell subpopulations in the human esophageal squamous cell carcinoma microenvironment
Here, we obtained a through epithelial cell atlas of ESCC at single-cell resolution, explored the role of epithelial cell in ESCC progression, and unveiled immunosuppressive signals to NK/T cells in promoting ESCC. Our findings expand the comprehension of epithelial cells and offer a theoretical guidance for future anti-epithelial cell treatment of ESCC.
Authors
- Yongwei Xie
- Li Guo (ORCID: https://orcid.org/0000-0001-6100-3481)
- Zhiyong Zeng
- Bo Wu (ORCID: https://orcid.org/0000-0003-4556-0477)
- Chenxi Zhang (ORCID: https://orcid.org/0000-0001-6560-177X)
- Jingrong Yang
- Wencui Kong
Institutions
- Fujian Medical University (CN)
- 117th Hospital of People's Liberation Army (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38091
- Citations
- 3
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.72