Diagnostic Accuracy of Circulating Tumor HPV DNA Testing in Patients With a Lateral Neck Mass

In this diagnostic study of patients presenting with a lateral neck mass, circulating TTMV-HPV DNA demonstrated excellent diagnostic test characteristics for the detection of HPV-OPSCC. Such testing may have particular utility for patients in whom obtaining adequate tissue is problematic, as is often the case with cystic neck masses and unknown primary tumors.

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Publication Details

Journal
JAMA Otolaryngology–Head & Neck Surgery
Published
2024-09-19
DOI
https://doi.org/10.1001/jamaoto.2024.2702
Citations
6
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
3.48
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article

Diagnostic Accuracy of Circulating Tumor HPV DNA Testing in Patients With a Lateral Neck Mass

Kunal K. Sindhu, Michael H. Berger, Eric Michael Genden, Joshua Barlow et al.
6 citations
JAMA Otolaryngology–Head & Neck Surgery
Head and Neck Cancer Studies
3.48
article

Diagnostic Accuracy of Circulating Tumor HPV DNA Testing in Patients With a Lateral Neck Mass

Kunal K. Sindhu, Michael H. Berger, Eric Michael Genden, Joshua Barlow, Rocco M. Ferrandino, Krzysztof J. Misiukiewicz, Brandon Gold, Richard L. Bakst, Scott A. Roof, Raymond Liu Chai, Marshall R. Posner, Mohemmed N. Khan, William H. Westra, Marita S. Teng, Daniel Kraft
article en
6 citations

Abstract

In this diagnostic study of patients presenting with a lateral neck mass, circulating TTMV-HPV DNA demonstrated excellent diagnostic test characteristics for the detection of HPV-OPSCC. Such testing may have particular utility for patients in whom obtaining adequate tissue is problematic, as is often the case with cystic neck masses and unknown primary tumors.

JAMA Otolaryngology–Head & Neck SurgeryVol. 150(12)
Icahn School of Medicine at Mount Sinai (US)
Openalex Percentile: Top 7%
Head and Neck Cancer Studies
3.48
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