Placental mosaicism for autosomal trisomies: comprehensive follow-up of 528 Danish cases (1983–2021)
Introducing cFTS increased the detection of placental mosaicism with fetal involvement and CPM with adverse outcome. In cases of mosaicism in CVSs, the risk of fetal involvement and adverse outcomes varied considerably between chromosomes. Importantly, adverse outcomes were seen in CPM for many trisomies besides trisomy 16.
Authors
- Ida Vogel (ORCID: https://orcid.org/0000-0002-1125-0393)
- Simon Horsholt Thomsen
- Naja Becher (ORCID: https://orcid.org/0000-0003-1264-1940)
- Ida Charlotte Bay Lund (ORCID: https://orcid.org/0000-0001-5480-220X)
- Iben Bache (ORCID: https://orcid.org/0000-0001-7562-8546)
Institutions
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- American Journal of Obstetrics & Gynecology MFM
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.ajogmf.2024.101497
- Citations
- 5
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 5.55