OSA symptom subtypes and hypoxic burden independently predict distinct cardiovascular outcomes
OSA symptom subtypes and HB are independently associated with MACE and cardiovascular mortality, respectively. Thus, both are important for understanding OSA-related cardiovascular risk. Future studies using clinical samples including OSA therapy information that incorporate symptom subtypes and novel biomarkers, such as HB, could improve predictive models for cardiovascular disease risk.
Authors
- Brendan T Keenan (ORCID: https://orcid.org/0000-0002-9070-847X)
- Diego R. Mazzotti (ORCID: https://orcid.org/0000-0003-3924-9199)
- Ulysses J. Magalang (ORCID: https://orcid.org/0000-0002-5052-2494)
- Jesse Mindel
- Thomas Penzel (ORCID: https://orcid.org/0000-0002-4304-0112)
- Allan I Pack (ORCID: https://orcid.org/0000-0002-2879-0484)
- Philip de Chazal (ORCID: https://orcid.org/0000-0002-2091-207X)
- Magdy Younes (ORCID: https://orcid.org/0000-0001-5764-7786)
Institutions
- The University of Sydney (AU)
- Charles Sturt University (AU)
- The Ohio State University Wexner Medical Center (US)
- University of Kansas Medical Center (US)
- University of Manitoba (CA)
- Charité - Universitätsmedizin Berlin (DE)
- University of Pennsylvania (US)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1183/23120541.00511-2024
- Citations
- 9
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- American Heart Association
- American Academy of Sleep Medicine Foundation
- NIH Clinical Center