Amide proton transfer and apparent diffusion coefficient analysis reveal susceptibility of brain regions to neonatal hypoxic-ischemic encephalopathy
APTw and ADC are effective in detecting HIE, with APTw being more sensitive. The right anterior temporal lobe is particularly affected by HIE, with significant changes in APTw and ADC values and a positive correlation between them. This suggests that temporal lobe damage may be critical in the long-term neurological consequences of HIE.
Authors
- Xuehua Peng
- Ya‐Jing Ye (ORCID: https://orcid.org/0000-0002-1970-6447)
- Xiaohu Zhu
- Jian Li (ORCID: https://orcid.org/0000-0002-5239-9469)
- Baiqi Zhu
- Yu Guo (ORCID: https://orcid.org/0000-0001-5135-2928)
Institutions
- Wuhan Children's Hospital (CN)
- Wuhan Medical Center for Women and Children (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38062
- Citations
- 1
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- Natural Science Foundation of Hubei Province
- Health and Family Planning Commission of Wuhan Municipality