Sequential vs. concurrent systemic therapies in combination with FOLFOX-HAIC for locally advanced hepatocellular carcinoma: a single-center, real-world cohort study

Our study revealed that sequential systemic ICIs and TKIs in combination with FOLFOX-HAIC provides similar long-term prognosis and better tolerability compared to concurrent therapy for locally advanced HCC patients. Prospective studies with a larger sample size and longer follow-up are required to validate these findings.

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Publication Details

Journal
BMC Cancer
Published
2024-09-19
DOI
https://doi.org/10.1186/s12885-024-12940-0
Citations
7
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
2.59

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article

Sequential vs. concurrent systemic therapies in combination with FOLFOX-HAIC for locally advanced hepatocellular carcinoma: a single-center, real-world cohort study

Dandan Hu, Yangxun Pan, Huilan Zeng, Yaojun Zhang et al.
7 citations
BMC Cancer
Hepatocellular Carcinoma Treatment and Prognosis
2.59
article

Sequential vs. concurrent systemic therapies in combination with FOLFOX-HAIC for locally advanced hepatocellular carcinoma: a single-center, real-world cohort study

Dandan Hu, Yangxun Pan, Huilan Zeng, Yaojun Zhang, Wa Xie, Minshan Chen, Zhenyun Yang, Zhiwen Hu, Li‐Yang Sun, Zhongguo Zhou
article en
7 citations

Abstract

Our study revealed that sequential systemic ICIs and TKIs in combination with FOLFOX-HAIC provides similar long-term prognosis and better tolerability compared to concurrent therapy for locally advanced HCC patients. Prospective studies with a larger sample size and longer follow-up are required to validate these findings.

BMC CancerVol. 24(1)
Sun Yat-sen University (CN), Sun Yat-sen University Cancer Center (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 10%
Hepatocellular Carcinoma Treatment and Prognosis
2.59
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