Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies

In the post-ETI period, psychiatric ADRs are the most prevalent ADR reported via the Yellow Card scheme. Despite an unclear mechanism, there is significant clinical relevance in counselling and monitoring regarding psychiatric effects of CFTR modulator therapy.

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Publication Details

Journal
Journal of Cystic Fibrosis
Published
2024-09-19
DOI
https://doi.org/10.1016/j.jcf.2024.09.010
Citations
7
Primary Topic
Cystic Fibrosis Research Advances
Type
article
Field-Weighted Citation Impact
2.93
Controls
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article

Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies

Freddy Frost, D. Nazareth, Kevin W Southern, Jacob O'Connor et al.
7 citations
Journal of Cystic Fibrosis
Cystic Fibrosis Research Advances
2.93
article

Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies

Freddy Frost, D. Nazareth, Kevin W Southern, Jacob O'Connor, Dennis Wat
article en
7 citations

Abstract

In the post-ETI period, psychiatric ADRs are the most prevalent ADR reported via the Yellow Card scheme. Despite an unclear mechanism, there is significant clinical relevance in counselling and monitoring regarding psychiatric effects of CFTR modulator therapy.

Journal of Cystic FibrosisVol. 24(1)
University of Liverpool (GB), Liverpool Heart and Chest Hospital NHS Trust (GB), Liverpool Heart and Chest Hospital (GB), Alder Hey Children's Hospital (GB)
Good health and well-being
Openalex Percentile: Top 8%
Cystic Fibrosis Research Advances
2.93
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