EZH2 mutation is associated with the development of visceral metastasis by enhancing proliferation and invasion and inhibiting apoptosis in breast cancer cells
EZH2 mutation is associated with VM development in breast cancer patients. The EZH2<sup>K515R</sup> mutation leads to VM and a poor prognosis by enhancing proliferation and invasion and inhibiting apoptosis in breast cancer cells.
Authors
- Nani Li (ORCID: https://orcid.org/0000-0001-5693-1152)
- Hong Yi (ORCID: https://orcid.org/0009-0003-9168-6780)
- Xiufeng Wu (ORCID: https://orcid.org/0000-0001-8007-7072)
- Mulan Chen (ORCID: https://orcid.org/0000-0001-7854-0910)
- Weiwei Huang (ORCID: https://orcid.org/0000-0002-9947-4083)
- Fan Wu (ORCID: https://orcid.org/0000-0001-7686-2887)
- Lin Lin (ORCID: https://orcid.org/0000-0001-6304-2249)
- Jian Liu (ORCID: https://orcid.org/0000-0002-1447-0973)
- Kan Chen (ORCID: https://orcid.org/0000-0003-4429-9043)
- Xinhua Chen (ORCID: https://orcid.org/0000-0003-0429-3317)
- Minjin You
- Lili Wang (ORCID: https://orcid.org/0009-0009-1660-3678)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1186/s12885-024-12950-y
- Citations
- 3
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Natural Science Foundation of Fujian Province
- Fujian Medical University