Characteristics and clinical outcomes of breast cancer in young BRCA carriers according to tumor histology
In this large global cohort of young BRCA carriers with breast cancer, the incidence of pure lobular histology was low and associated with higher disease stage at diagnosis, luminal-like disease and BRCA2 PVs. Histology did not appear to impact prognosis.
Authors
- Shani Paluch–Shimon (ORCID: https://orcid.org/0000-0002-6677-2199)
- Nerea Lopetegui‐Lia (ORCID: https://orcid.org/0000-0002-6207-2371)
- Anne‐Sophie Hamy (ORCID: https://orcid.org/0000-0003-4430-3022)
- Hampig Raphaël Kourié (ORCID: https://orcid.org/0000-0002-2502-5402)
- Fabio Puglisi (ORCID: https://orcid.org/0000-0003-0573-4938)
- Elene Mariamidze (ORCID: https://orcid.org/0000-0001-8838-9193)
- Roberto Borea (ORCID: https://orcid.org/0000-0001-5403-0916)
- Claudio Vernieri (ORCID: https://orcid.org/0000-0003-1577-8176)
- Françoise Derouane (ORCID: https://orcid.org/0000-0002-0199-1366)
- Katarzyna Pogoda (ORCID: https://orcid.org/0000-0002-9902-711X)
- Laura De Marchis (ORCID: https://orcid.org/0000-0003-2195-7955)
- Eva Blondeaux (ORCID: https://orcid.org/0000-0001-9566-4579)
- Thomas Renaud (ORCID: https://orcid.org/0000-0002-4895-6090)
- Alberta Ferrari (ORCID: https://orcid.org/0000-0003-2525-3787)
- Kathryn J. Ruddy (ORCID: https://orcid.org/0000-0001-6298-332X)
- Guilherme Nader Marta (ORCID: https://orcid.org/0000-0001-7864-3637)
- Mariya Rozenblit (ORCID: https://orcid.org/0000-0002-8874-6688)
- Ann H. Partridge (ORCID: https://orcid.org/0000-0002-4722-4824)
- Alexios Matikas (ORCID: https://orcid.org/0000-0002-4122-9624)
- Joanna Kufel-Grabowska (ORCID: https://orcid.org/0000-0002-5724-9961)
- Estela Carrasco (ORCID: https://orcid.org/0000-0003-1964-7675)
- Marco Bruzzone (ORCID: https://orcid.org/0000-0002-8821-4542)
- Laura Cortesi (ORCID: https://orcid.org/0000-0001-8950-8561)
- Christine Rousset‐Jablonski (ORCID: https://orcid.org/0000-0001-7087-5687)
- Sabine C. Linn (ORCID: https://orcid.org/0000-0001-5541-0347)
- Robert Fruscio (ORCID: https://orcid.org/0000-0001-5688-2194)
- Francesco Atzori (ORCID: https://orcid.org/0000-0002-8211-0363)
- Lazar Popović (ORCID: https://orcid.org/0000-0002-3278-6875)
- Wanyuan Cui (ORCID: https://orcid.org/0000-0002-5077-6814)
- Roberta Di Rocco
- Mirco Pistelli (ORCID: https://orcid.org/0000-0002-9289-8537)
- Maria Vittoria Dieci (ORCID: https://orcid.org/0000-0002-3967-9861)
- Evandro de Azambuja (ORCID: https://orcid.org/0000-0001-9501-4509)
- Elisa Agostinetto (ORCID: https://orcid.org/0000-0003-0295-7511)
- Matteo Lambertini (ORCID: https://orcid.org/0000-0003-1797-5296)
- Rinat Bernstein‐Molho (ORCID: https://orcid.org/0000-0002-4068-9514)
- Jyoti Bajpai (ORCID: https://orcid.org/0000-0001-7657-3460)
- Camila Chiodi (ORCID: https://orcid.org/0009-0001-7042-383X)
- Hyo Jung Kim (ORCID: https://orcid.org/0000-0002-3514-1247)
- F Giugliano
- D Aguilar Y Mendez
Institutions
- Ulsan College (KR)
- Hebron University (PS)
- Cleveland Clinic (US)
- Université Libre de Bruxelles (BE)
- Mayo Clinic (US)
- Karolinska University Hospital (SE)
- Inserm (FR)
- University of Novi Sad (RS)
- Saint Joseph University (LB)
- Hebrew University of Jerusalem (IL)
- Homi Bhabha National Institute (IN)
- Université Paris Cité (FR)
- University of Pavia (IT)
- Sheba Medical Center (IL)
- Hadassah Medical Center (IL)
- Tata Memorial Hospital (IN)
- Policlinico Umberto I (IT)
- Peter MacCallum Cancer Centre (AU)
- Asan Medical Center (KR)
- Jewish General Hospital (CA)
- Institut Jules Bordet (BE)
- Institut Gustave Roussy (FR)
- Yale Cancer Center (US)
- The Netherlands Cancer Institute (NL)
- Jerusalem Multidisciplinary College (IL)
- Yale University (US)
- University of Ulsan (KR)
- Hôpital Femme Mère Enfant (FR)
- Hospices Civils de Lyon (FR)
- Hospital Zambrano Hellion (MX)
- Azienda Ospedaliero Universitaria Ospedali Riuniti (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Istituto Oncologico Veneto (IT)
- Dana-Farber Cancer Institute (US)
- Institute of Public Health of Vojvodina (RS)
- Azienda Ospedaliero-Universitaria Cagliari (IT)
- Centre de Recherche en Cancérologie de Lyon (FR)
- Centro di Riferimento Oncologico (IT)
- Institut Bergonié (FR)
- Ospedale Misericordia - Grosseto (IT)
- Ospedale Policlinico San Martino (IT)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- European Institute of Oncology (IT)
- University of Milano-Bicocca (IT)
- Gdańsk Medical University (PL)
- Institut Curie (FR)
- Sapienza University of Rome (IT)
- Tecnológico de Monterrey (MX)
- KU Leuven (BE)
Publication Details
- Journal
- ESMO Open
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1016/j.esmoop.2024.103714
- Citations
- 6
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.30
Funders
- National Breast Cancer Foundation
- Cancer Australia
- Korea Health Industry Development Institute
- Associazione Italiana per la Ricerca sul Cancro
- European Society for Medical Oncology
- Medical Research Council
- National Health and Medical Research Council
- Tata Memorial Centre