Comparison of Various Low Density Lipoprotein Cholesterol Calculators: Is It Time for the Friedewald Equation to Go in India?

Sampson's equation improves the accuracy of the indirectly calculated LDL-c compared to Friedewald's equation. The FLDL-c is estimated falsely low at LDL-c ≤ 70 mg/dL, giving a lower sense of LDL-c goal being achieved, and these patients will be undertreated. By switching to Sampson's equation, 9% in the LDL-c ≤ 70 mg/dL and 5% in the LDL-c > 70 mg/dL can be correctly classified. The shift to Sampson's equation requires a simple formula change and can be easily embraced in India-a small change but in the right direction.

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Journal
Journal of the Association of Physicians of India
Published
2024-09-01
DOI
https://doi.org/10.59556/japi.72.0645
Citations
1
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
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article
Field-Weighted Citation Impact
0.36
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article

Comparison of Various Low Density Lipoprotein Cholesterol Calculators: Is It Time for the Friedewald Equation to Go in India?

Prabhakar Dorairaj, C. Hemnath, Malini Sreyan, R Perumalraja et al.
1 citations
Journal of the Association of Physicians of India
Diabetes, Cardiovascular Risks, and Lipoproteins
0.36
article

Comparison of Various Low Density Lipoprotein Cholesterol Calculators: Is It Time for the Friedewald Equation to Go in India?

Prabhakar Dorairaj, C. Hemnath, Malini Sreyan, R Perumalraja, P G Vijayakumar, Ramadesikan Veeraraghavan Kuppuswamy
article en
1 citations

Abstract

Sampson's equation improves the accuracy of the indirectly calculated LDL-c compared to Friedewald's equation. The FLDL-c is estimated falsely low at LDL-c ≤ 70 mg/dL, giving a lower sense of LDL-c goal being achieved, and these patients will be undertreated. By switching to Sampson's equation, 9% in the LDL-c ≤ 70 mg/dL and 5% in the LDL-c > 70 mg/dL can be correctly classified. The shift to Sampson's equation requires a simple formula change and can be easily embraced in India-a small change but in the right direction.

Journal of the Association of Physicians of IndiaVol. 72(9)
Sundaram Medical Foundation (IN), Apollo Hospitals (IN), Ashwini Hospital (IN), VRR Diagnostic Services (India) (IN), Apollo Hospitals (IN), Dr. Mehta's Children's Hospital (IN)
Openalex Percentile: Top 34%
Diabetes, Cardiovascular Risks, and Lipoproteins
0.36
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Comparison of Various Low Density Lipoprotein Cholesterol Calculators: Is It Time for the Friedewald Equation to Go in India? — Prabhakar Dorairaj, C. Hemnath, et al. · Journal of the Association of Physicians of India (2024) | TGRS Research Map | TGRS