Role of quantitative imaging biomarkers in an early FDG-PET/CT for detection of immune-related adverse events in melanoma patients: a prospective study
Early time point <sup>18</sup>F-FDG PET/CT at W4 did not lead to statistically significant earlier detection of irAE. However, organ <sup>18</sup>F-FDG uptake as quantified by SUV<sub>X%</sub> proved to be a consistent QIB of irAE. To better assess the role of <sup>18</sup>F-FDG PET/CT in irAE detection, the time evolution of <sup>18</sup>F-FDG PET/CT quantifiable inflammation would be of essence, only achievable in multi centric studies.
Authors
- Katja Škalic
- Nežka Hribernik (ORCID: https://orcid.org/0000-0002-6468-9906)
- Robert Jeraj (ORCID: https://orcid.org/0000-0002-2192-2931)
- Andrej Studen (ORCID: https://orcid.org/0000-0002-1254-9530)
- Martina Reberšek (ORCID: https://orcid.org/0000-0002-7025-8571)
- Katarina Zevnik (ORCID: https://orcid.org/0000-0001-5665-4837)
- Katja Strašek (ORCID: https://orcid.org/0009-0004-6115-1512)
- Daniel T Huff (ORCID: https://orcid.org/0000-0001-9792-4119)
Institutions
- University of Wisconsin–Madison (US)
- University of Ljubljana (SI)
- Jožef Stefan Institute (SI)
- Institute of Oncology Ljubljana (SI)
- University of Wisconsin Carbone Cancer Center (US)
Publication Details
- Journal
- Radiology and Oncology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2478/raon-2024-0045
- Citations
- 3
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Javna Agencija za Raziskovalno Dejavnost RS