Laser Ablation of Periventricular Nodular Heterotopia for Medically Refractory Epilepsy
PVNH plays a central role in seizure genesis as revealed by dense recordings and selective targeting by LITT. MRgLITT represents a transformative technological advance in PVNH-associated epilepsy with seizure control outcomes consistent with those seen in focal lesional epilepsies. In localized unilateral cases and otherwise normal imaging, PVNH ablation without invasive recordings may be considered, and this approach deserves to be explored further. ANN NEUROL 2024;96:1174-1184.
Authors
- Stephen A. Thompson (ORCID: https://orcid.org/0000-0002-1906-8510)
- Ryan McCormack
- Nitin Tandon (ORCID: https://orcid.org/0000-0002-2752-2365)
- Giridhar P. Kalamangalam (ORCID: https://orcid.org/0000-0002-0178-4332)
- Katherine M. Harris (ORCID: https://orcid.org/0000-0003-0466-646X)
- Nuria Lacuey (ORCID: https://orcid.org/0000-0002-6067-7414)
- Samden D. Lhatoo (ORCID: https://orcid.org/0000-0001-8626-1137)
- Arjun Chandran (ORCID: https://orcid.org/0009-0000-1072-2523)
- Sandipan Pati (ORCID: https://orcid.org/0000-0003-4171-2138)
- Zhouxuan Li
Institutions
- University of Florida (US)
- University of Texas Health Science Center at Dallas (US)
- Memorial Hermann–Texas Medical Center (US)
- Neurological Surgery (US)
- The University of Texas Health Science Center at Houston (US)
- McMaster University (CA)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1002/ana.27059
- Citations
- 8
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 2.15