Assessing the Relationship between Personality Traits and Clinical Aspects in Individuals with Multiple Sclerosis

Personality traits significantly impact chronic diseases, affecting disease management, coping strategies, psychological well-being, and overall quality of life. People with Multiple Sclerosis (MS) often exhibit dysfunctional personality traits associated with negative disease outcomes, including personality changes and disorders. Our study explored personality traits and their connection to clinical aspects and cognitive functioning in MS patients. We used two assessment tools: the NEO-FFI and the Lüscher Color Test, which is based on color preferences. The aim was to investigate the applicability of the Lüscher Color Test in MS patients. The study included 20 participants from the Swiss Multiple Sclerosis Cohort. The results showed elevated scores in neuroticism, openness, agreeableness, and conscientiousness in MS patients, while there was no effect for extraversion. A significant positive correlation was found between neuroticism and the preference for green-blue color shades, as well as a rejection of orange-reddish color shades in the Lüscher Color Test, indicating avoidance of stimulation and engagement. Another notable positive association was found between openness and the preference for lighter shades in the Lüscher Color Test. Although this relation did not reach the level of statistical significance, it suggests a potential trend. Neuroticism on its own predicted anxiety and fatigue, while the preference for lighter shades in the Lüscher Color Test correlated with EDSS scores. No significant correlations were found between personality traits and cognitive aspects. Despite the limitations of this study, our results highlight the importance of assessing personality traits in MS patients, using either the NEO-FFI or the Lüscher Color Test, to improve treatment strategies and explore emotional conflicts related to the disease.