Rare cases of primarily infected kidney graft transplantation with the development of purulent complications

Background. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxis. Objective. To demonstrate the need for immediate removal of a primary infected kidney graft in the event of local purulent complications due to the rapid development of sepsis in immunocompromised patients. Results. The paper describes a clinical course of the infectious process in two kidney recipients each of whom underwent transplantation of a primary infected graft from a single donor, taking into consideration the transplantectomy timing and the treatment outcomes. Conclusion. The Case Report shows the need for immediate transplantectomy in a kidney graft recipient when local purulent complications are detected with confirmed primary infection of the graft due to a high risk of the rapid development of sepsis and threat to life.

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Publication Details

Journal
Transplantologiya The Russian Journal of Transplantation
Published
2024-09-17
DOI
https://doi.org/10.23873/2074-0506-2024-16-3-353-363
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
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article

Rare cases of primarily infected kidney graft transplantation with the development of purulent complications

К. Е. Лазарева, И. В. Дмитриев, N. S. Zhuravel, А. Г. Балкаров et al.
Transplantologiya The Russian Journal of Transplantation
Renal Transplantation Outcomes and Treatments
article

Rare cases of primarily infected kidney graft transplantation with the development of purulent complications

К. Е. Лазарева, И. В. Дмитриев, N. S. Zhuravel, А. Г. Балкаров, D. V. Lonshakov, Н. В. Шмарина, V. V. Smirnova
article en

Abstract

Background. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxis. Objective. To demonstrate the need for immediate removal of a primary infected kidney graft in the event of local purulent complications due to the rapid development of sepsis in immunocompromised patients. Results. The paper describes a clinical course of the infectious process in two kidney recipients each of whom underwent transplantation of a primary infected graft from a single donor, taking into consideration the transplantectomy timing and the treatment outcomes. Conclusion. The Case Report shows the need for immediate transplantectomy in a kidney graft recipient when local purulent complications are detected with confirmed primary infection of the graft due to a high risk of the rapid development of sepsis and threat to life.

Transplantologiya The Russian Journal of TransplantationVol. 16(3)
Research Medical Center (US)
Openalex Percentile: Top 77%
Renal Transplantation Outcomes and Treatments
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Rare cases of primarily infected kidney graft transplantation with the development of purulent complications — К. Е. Лазарева, И. В. Дмитриев, et al. · Transplantologiya The Russian Journal of Transplantation (2024) | TGRS Research Map | TGRS