P088 VASCULAR HYPERREACTIVITY IS RELATED TO SHORTENING FRACTION AND LEFT VENTRICULAR MASS IN YOUNG NORMOTENSIVES

Summary Background and objective: Vascular reactivity has been related to left ventricular hypertrophy, but there are insufficient data on whether this relationship involves left ventricular (LV) contractility. Our aim was to relate the degree of cardiovascular reactivity to LV mass and contractility. Methods: A cross-sectional study was carried out in normotensive men aged 16-40 years, divided into 2 groups of 30 individuals according to the degree of vascular reactivity determined by the sustained weight test. The LV mass index (LVMI) and the shortening fraction were determined by transthoracic echocardiography. Results: LVMI was found to be significantly higher in hyperreactive than in normoreactive patients (123.57 g/m2 vs. 105.10 g/m2 p<0.01) and the shortening fraction in hyperreactive patients was significantly lower than in normoreactive patients (31.21% vs. 33.78% p<0.05). This difference increased in the subgroup of hyper-reactive patients with left ventricular hypertrophy and disappeared in hyper-reactive patients without hypertrophy when compared in each case with normoreactive patients. Conclusions: Hyperreactivity status is related to lower shortening fraction and greater left ventricular mass in young normotensive males.