P123 ASSOCIATION OF VERY SHORT INTERNVAL HEART RATE MEAN ABSOLUTE DEVIATION WITH HYPERTENSION: FROM NHANES 2017- 2020

Background: Heart Rate Variability (HRV) has recently gained popularity as an indicator of cardiovascular health. However, the association between the Mean Absolute Deviation of Heart Rate (HR-AMD), one of the HRV parameters, and Hypertension (HT), especially in very short intervals, in a nationally representative population, remains unknown. This study aims to investigate the relationship between HR-AMD and HT in the general population. Methods: A cross-sectional analysis of data from the 2017-2020 National Health and Nutrition Examination Survey (NHANES) was conducted to explore the association. Participants had their heart rate measured three consecutive times, 60 seconds apart, using a digital device. HR-AMD was calculated and categorized into quartiles. HT data were collected through self-reporting. Logistic regression models, comparing participants with HR-MAD in Q1 to those in higher quartiles and adjusting for demographics and comorbidities, were analyzed. Results: The study included 9,204 adult participants with a mean HR-AMD of 0.02 beats per minute. Among them, 3,554(38.61%) experienced HT. In the general population, hypertension is lower in Q2-Q4, with statistically significant differences noted in Q2 with Odd ratio (OR) 0.80. After stratification by race and diabetic status (DM), there was a non-statistically significant negative association of 0.90 times with HT in Q2 of HR-AMD among White participants, while among Black participants, the OR were statistically significantly lower at 0.70 times. There also was a non-statistically significant negative association of 0.91 times with HT in Q2 of HR-AMD among DM individuals, while among non-DM individuals, the OR were statistically significantly lower at 0.78 times. Conclusions: A very short interval HR-AMD shows a negative association with HT in the general population, especially statistically significant in Q2. The greater negative associations only in black and non DM populations suggest that DM status and race may act as effect modifiers in the Q2 of HR-AMD. Further studies are required for a deeper understanding of this relationship.