O94 MOST EFFECTIVE EXERCISE INTERVENTIONS FOR REDUCING SHORT-TERM BLOOD PRESSURE VARIABILITY: A META-ANALYSIS

Objective: Blood pressure variability (BPV) is a risk factor for cardiovascular disease. Growing evidence suggests that exercise plays a critical role in reducing BPV. Hence, this study aimed to examine the specific types of exercise that are most effective in reducing BPV. Design and Method: A literature search was conducted across electronic databases including MEDLINE, Embase, and PsycINFO from their inception to February 2024. The assessment of short-term BPV involved the utilization of diverse equations, such as standard deviations, coefficient of variation, and average real variability, as reported in the included studies. Regarding the heterogeneity arising from the varied calculation methods, standardized mean differences were employed. The heterogeneity was carried out using the I 2 statistic, with a fixed-effect Mantel-Haenszel model applied in cases where I 2 < 50%, and a random-effect model employed when I 2 > 50%. Results: A total of 8,359 literature records were identified from the electronic databases, 21 articles met the inclusion criteria and were included in this study. Among these, 12 articles were randomized controlled trials (RCTs), 4 were pre-post clinical trials, 2 were cross-sectional studies, and 3 were cohort studies. Among the RCTs, 11 studies focused on short-term blood pressure variability (BPV) as the primary outcome, while the remaining 2 RCTs examined long-term BPV. The collective analysis of 529 participants revealed that exercise interventions resulted in significant improvements in short-term SBPV (standardized mean difference [SMD] [95% CI] = -0.56 [-1.04 to -0.09]) and DBPV (-0.62 [-1.02 to -0.22]). Specifically, resistance exercise demonstrated notable reductions in SBPV (-0.62 [-1.15 to -0.10]), while no significant effects were observed on DBPV (0.04 [-0.54 to 0.62]). Conversely, aerobic exercise exhibited beneficial effects on both SBPV (-0.57 [-1.16 to 0.01]) and DBPV (-0.82 [-1.43 to -0.21]) (Table 1). Conclusion: Exercise interventions showed significant improvements in short-term SBPV and DBPV, with resistance exercise specifically reducing SBPV and aerobic exercise benefiting both SBPV and DBPV.