Research of recombinant influenza A virus as a vector for <i>Mycoplasma pneumoniae</i> P1a and P30a
The recombinant viruses rFLU-P1a and rFLU-P30a which carried the advantaged immune regions of the P1 and P30 genes in MP were successfully constructed and identified. And the genetic stability of rFLU-P1a or rFLU-P30a was relatively high. The typical and complete morphology of influenza virus was observed under the electron microscope. Our research provided a foundation for the further development of MP vaccines for human.
Authors
- Ma Linna
- Yu Liang (ORCID: https://orcid.org/0000-0003-3701-4994)
- Jia Tan (ORCID: https://orcid.org/0000-0001-6482-818X)
- Guoyang Liao (ORCID: https://orcid.org/0000-0001-9566-9046)
- Yongbo Wang (ORCID: https://orcid.org/0000-0003-2030-7029)
- XU Ya (ORCID: https://orcid.org/0000-0002-9779-0672)
- Yang Shengjun
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Kunming Medical University (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/iid3.70021
- Citations
- 1
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Kunming Medical University
- Yunnan Provincial Science and Technology Department