P096 LEFT VENTRICULAR HYPERTROPHY PATTERNS IN HYPERTENSIVE SUBJECTS WITH CHRONIC KIDNEY DISEASE

Background and Objective. A left ventricular (LV) geometric pattern classification based on its concentrically and dilatation has been recommended for clinical practice use. However, there is no clear data demonstrating whether such categorization could improve the diagnostic strategy of adult hypertensives with chronic kidney disease (CKD). The aim of the study was to analyze LV hypertensive patterns in adult individuals with arterial hypertension and CKD. Methods. We studied 56 hypertension in-treated individuals with sinus rhythm (mean age, 62 [95% CI, 58–65] years, 46.4% women) using transthoracic echocardiogram (Esaote, MyLabEight). There were no pregnant women and objects engaged in professional sport. LV geometric patterns classified according to LV mass, volume, and relative wall thickness were analyzed. Moreover, CKD stages were studied with glomerular filtration rate calculation (the CKD-EPI creatinine equation). Results. Concentric hypertrophy (24/56) for 1-4 CKD stages, mixed hypertrophy (1/56) for the 4th CKD stage, dilated hypertrophy (12/56) for 2-3 CKD stages, normal/physiological hypertrophy (14/56) for 1-3 CKD stages, and the eccentric hypertrophy (4/56) for 1-3 CKD stages were detected. Objects with the stage 1 CKD had mainly normal/physiological hypertrophy (44.4%), with stages 2 and 3 CKD had concentric hypertrophy (43% and 48%, respectively), and with the 4 CKD had the same rate of concentric and mixed hypertrophy (50%). Conclusions. It was found different LV hypertensive geometric patterns among hypertensive individuals with CKD. Unexpectedly, there was a large amount of the normal/physiological hypertrophy pattern in arterial hypertension individuals with CKD, mainly with the stage 3.

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Publication Details

Journal
Journal of Hypertension
Published
2024-09-01
DOI
https://doi.org/10.1097/01.hjh.0001063256.75570.d6
Primary Topic
Hormonal Regulation and Hypertension
Type
article
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article

P096 LEFT VENTRICULAR HYPERTROPHY PATTERNS IN HYPERTENSIVE SUBJECTS WITH CHRONIC KIDNEY DISEASE

В. В. Сыволап, Л. В. Лукашенко, S. P. Zhemanyuk
Journal of Hypertension
Hormonal Regulation and Hypertension
article

P096 LEFT VENTRICULAR HYPERTROPHY PATTERNS IN HYPERTENSIVE SUBJECTS WITH CHRONIC KIDNEY DISEASE

В. В. Сыволап, Л. В. Лукашенко, S. P. Zhemanyuk
article en

Abstract

Background and Objective. A left ventricular (LV) geometric pattern classification based on its concentrically and dilatation has been recommended for clinical practice use. However, there is no clear data demonstrating whether such categorization could improve the diagnostic strategy of adult hypertensives with chronic kidney disease (CKD). The aim of the study was to analyze LV hypertensive patterns in adult individuals with arterial hypertension and CKD. Methods. We studied 56 hypertension in-treated individuals with sinus rhythm (mean age, 62 [95% CI, 58–65] years, 46.4% women) using transthoracic echocardiogram (Esaote, MyLabEight). There were no pregnant women and objects engaged in professional sport. LV geometric patterns classified according to LV mass, volume, and relative wall thickness were analyzed. Moreover, CKD stages were studied with glomerular filtration rate calculation (the CKD-EPI creatinine equation). Results. Concentric hypertrophy (24/56) for 1-4 CKD stages, mixed hypertrophy (1/56) for the 4th CKD stage, dilated hypertrophy (12/56) for 2-3 CKD stages, normal/physiological hypertrophy (14/56) for 1-3 CKD stages, and the eccentric hypertrophy (4/56) for 1-3 CKD stages were detected. Objects with the stage 1 CKD had mainly normal/physiological hypertrophy (44.4%), with stages 2 and 3 CKD had concentric hypertrophy (43% and 48%, respectively), and with the 4 CKD had the same rate of concentric and mixed hypertrophy (50%). Conclusions. It was found different LV hypertensive geometric patterns among hypertensive individuals with CKD. Unexpectedly, there was a large amount of the normal/physiological hypertrophy pattern in arterial hypertension individuals with CKD, mainly with the stage 3.

Journal of HypertensionVol. 42(Suppl 3)
Zaporizhzhia State Medical and Pharmaceutical University (UA)
Openalex Percentile: Top 76%
Hormonal Regulation and Hypertension
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