Causal association between hyperthyroidism and risk of gastroesophageal reflux or esophageal cancer: a bidirectional Mendelian randomization investigation

Our findings provided genetic evidence supporting bidirectional causal relationships between hyperthyroidism and GERD or esophageal cancer. These results substantiate certain discoveries from previous observational studies on a causal level and provide insight into relevant genetic susceptibility factors.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2024-09-17
DOI
https://doi.org/10.3389/fendo.2024.1411629
Citations
2
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.93

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article

Causal association between hyperthyroidism and risk of gastroesophageal reflux or esophageal cancer: a bidirectional Mendelian randomization investigation

Yingqiang Guo, Xingyu Zhu, H. Gan, Ming Li
2 citations
Frontiers in Endocrinology
Gastroesophageal reflux and treatments
0.93
article

Causal association between hyperthyroidism and risk of gastroesophageal reflux or esophageal cancer: a bidirectional Mendelian randomization investigation

Yingqiang Guo, Xingyu Zhu, H. Gan, Ming Li
article en
2 citations

Abstract

Our findings provided genetic evidence supporting bidirectional causal relationships between hyperthyroidism and GERD or esophageal cancer. These results substantiate certain discoveries from previous observational studies on a causal level and provide insight into relevant genetic susceptibility factors.

Frontiers in EndocrinologyVol. 15
Sichuan University (CN), West China Hospital of Sichuan University (CN)
National Research Foundation
Good health and well-being
Openalex Percentile: Top 24%
Gastroesophageal reflux and treatments
0.93
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