Quantitative and functional changes in platelets and fibrinogen following cardiopulmonary by-pass in children
Post-CPB coagulopathy is multifactorial and not solely attributed to hemodilution. It also involves functional changes in coagulation cascade components, which can be demonstrated by thromboelastometry and impedance aggregometry. Young children, patients requiring prolonged CPB surgery, or those experiencing hypothermia are particularly affected.
Authors
- David Longchamp (ORCID: https://orcid.org/0000-0002-8661-7575)
- Stefano Di Bernardo (ORCID: https://orcid.org/0000-0003-1977-3727)
- Marie‐Hélène Perez (ORCID: https://orcid.org/0000-0001-6173-3396)
- M. Plebani
- Pauline Lauwers
Institutions
- Mother Hospital (IN)
- University of Lausanne (CH)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-09-17
- DOI
- https://doi.org/10.3389/fped.2024.1453182
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00