A molecular epidemiological and transmission analysis of Clostridioides difficile using draft whole-genome sequencing in a single hospital
Additional culture tests and SNP analysis of C. difficile using draft WGS revealed silent transmission within the wards, particularly in cases involving frequent room changes and repeated admissions and discharges. Monitoring C. difficile transmission using WGS-based analysis could serve as a valuable marker in infection control management.
Authors
- Tadashi Maeda
- Yoshikazu Ishii (ORCID: https://orcid.org/0000-0002-1943-4648)
- Kohji Komori (ORCID: https://orcid.org/0000-0001-9659-3186)
- Kotaro Aoki (ORCID: https://orcid.org/0000-0002-9237-1217)
- Taito Miyazaki (ORCID: https://orcid.org/0000-0001-7239-8677)
- Yoshihisa Urita (ORCID: https://orcid.org/0000-0003-1740-0572)
- Sadako Yoshizawa (ORCID: https://orcid.org/0000-0001-5410-6511)
- Tateda Kazuhiro
Institutions
- Hiroshima University (JP)
- Toho University (JP)
- Toho University Omori Medical Center (JP)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1186/s12879-024-09841-9
- Citations
- 3
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Otsuka Pharmaceutical