Mechanism study of YangJing ZhongYu decoction on regulating mitochondrial dynamics of ovarian granular cells and improving diminished ovarian reserve

YJZYD promoted ovarian GC proliferation and mitochondrial fusion, suppressed cell apoptosis and mitochondrial fission, and effectively improved DOR in mice by activating the MAPK/ERK pathway, providing a theoretical basis for the clinical application value of YJZYD in DOR treatment.

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Publication Details

Journal
Journal of Ovarian Research
Published
2024-09-17
DOI
https://doi.org/10.1186/s13048-024-01506-0
Citations
5
Primary Topic
Reproductive Biology and Fertility
Type
article
Field-Weighted Citation Impact
2.71
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article

Mechanism study of YangJing ZhongYu decoction on regulating mitochondrial dynamics of ovarian granular cells and improving diminished ovarian reserve

Jilin Kuang, Ping Li
5 citations
Journal of Ovarian Research
Reproductive Biology and Fertility
2.71
article

Mechanism study of YangJing ZhongYu decoction on regulating mitochondrial dynamics of ovarian granular cells and improving diminished ovarian reserve

Jilin Kuang, Ping Li
article en
5 citations

Abstract

YJZYD promoted ovarian GC proliferation and mitochondrial fusion, suppressed cell apoptosis and mitochondrial fission, and effectively improved DOR in mice by activating the MAPK/ERK pathway, providing a theoretical basis for the clinical application value of YJZYD in DOR treatment.

Journal of Ovarian ResearchVol. 17(1)
Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Zero hunger
Openalex Percentile: Top 10%
Reproductive Biology and Fertility
2.71
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