High ratio of resident to exhausted CD4 + T cells predicts favorable prognosis and potentially better immunotherapeutic efficacy in hepatocellular carcinoma
The ratio of resident to exhausted CD4 + T cells shows promise as a potential biomarker for HCC prognosis and immunotherapy response and SASS6 may serve as a biomarker and therapeutic target for prognostic assessment of HCC.
Authors
- Shutong Liu (ORCID: https://orcid.org/0000-0003-0976-4966)
- Wenlong Jia (ORCID: https://orcid.org/0000-0002-7136-9919)
- Xinwei Han (ORCID: https://orcid.org/0000-0002-8411-6427)
- Jinxiang Lv
- Libo Wang (ORCID: https://orcid.org/0000-0003-3745-9459)
- Siyuan Weng (ORCID: https://orcid.org/0000-0001-6645-648X)
- Long Liu (ORCID: https://orcid.org/0000-0002-3473-2248)
- Hui Xu (ORCID: https://orcid.org/0000-0002-7366-3089)
- Zaoqu Liu (ORCID: https://orcid.org/0000-0002-0452-742X)
- Yuyuan Zhang
- Anning Zuo (ORCID: https://orcid.org/0009-0006-6779-8282)
- Yuhao Ba
Institutions
- Zhengzhou University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1186/s12885-024-12916-0
- Citations
- 3
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.85