From single-cell to spatial transcriptomics: decoding the glioma stem cell niche and its clinical implications
This study offers a comprehensive characterization of GSCs and their interactions with MDSCs, while presenting a robust GSCS. The findings offer new insights into glioma biology and identify potential therapeutic targets, particularly TUBA1C, aimed at improving patient outcomes.
Authors
- Lei Cao (ORCID: https://orcid.org/0000-0002-8666-0127)
- Xiaye Miao (ORCID: https://orcid.org/0009-0008-5499-6874)
- Lu Xu (ORCID: https://orcid.org/0000-0001-8447-135X)
- Xia Wang (ORCID: https://orcid.org/0000-0001-5787-2983)
- Hao Wu (ORCID: https://orcid.org/0009-0000-1030-9819)
Institutions
- Xuzhou Medical College (CN)
- Second People’s Hospital of Huai’an (CN)
- Northern Jiangsu People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-17
- DOI
- https://doi.org/10.3389/fimmu.2024.1475235
- Citations
- 15
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 3.51