Integrated single-cell and bulk RNA sequencing analysis reveal immune-related biomarkers in postmenopausal osteoporosis
JUN, HMOX1, CYSLTR2, TNFSF8, IL1R2, and SSTR5 may serve as promising molecular targets for diagnosing and subtyping patients with PMOP. These results offer novel perspectives on the early diagnosis of PMOP and the advancement of personalized immune-based therapies.
Authors
- Haonan Ni
- Ji-Kang Min (ORCID: https://orcid.org/0000-0002-2667-7509)
- Shouyu He (ORCID: https://orcid.org/0009-0009-9294-5143)
- Qianghua Zhang
- Shenyun Fang
- Weili Zhang
- Haidong Li (ORCID: https://orcid.org/0000-0002-2721-0337)
- Jilin Dai
Institutions
- Huzhou Normal University (CN)
- Third People's Hospital of Huzhou (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38022
- Citations
- 7
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- Natural Science Foundation of Zhejiang Province