Blood–brain barrier breakdown in dementia with Lewy bodies
BBB leakage is a common feature of DLB and possibly is even more severe than in the setting of AD for certain regions of the brain. BBB leakage appears to correlate with plasma Aβ1-42/Aβ1-40 ratio and dementia severity.
Authors
- Ziming Xu
- Yong Ji (ORCID: https://orcid.org/0000-0002-2191-6996)
- Jinghuan Gan (ORCID: https://orcid.org/0000-0002-8840-2834)
- Hao Lu (ORCID: https://orcid.org/0000-0002-0322-4400)
- Shuai Liu (ORCID: https://orcid.org/0000-0001-6984-7814)
- Hao Wu (ORCID: https://orcid.org/0000-0001-7096-2027)
- Yajie Wang (ORCID: https://orcid.org/0000-0001-7259-3886)
- Zhichao Chen (ORCID: https://orcid.org/0000-0002-9884-0002)
- Huijun Chen (ORCID: https://orcid.org/0000-0003-1158-5510)
- Zhihong Shi (ORCID: https://orcid.org/0000-0002-5743-5158)
Institutions
- Capital Medical University (CN)
- Tianjin Huanhu Hospital (CN)
- Beijing Friendship Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1186/s12987-024-00575-z
- Citations
- 6
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- National Natural Science Foundation of China
- Capital Medical University
- Tianjin Medical University
- Beijing Tian Tan Hospital, Capital Medical University