The iNKT cell ligand α-GalCer prevents murine septic shock by inducing IL10-producing iNKT and B cells
Overall, our results identify α-GalCer-mediated induction of IL10 by iNKT and B cells as a promising option for controlling the pathogenesis of postoperative sepsis.
Authors
- Tae-Cheol Kim (ORCID: https://orcid.org/0000-0002-9215-188X)
- Seokmann Hong (ORCID: https://orcid.org/0000-0002-4606-9789)
- Yun Hoo Park (ORCID: https://orcid.org/0000-0001-6944-8311)
- Luc Van Kaer (ORCID: https://orcid.org/0000-0001-5275-2309)
- Hyun Jung Park (ORCID: https://orcid.org/0000-0002-8547-156X)
- Sung Won Lee (ORCID: https://orcid.org/0000-0003-1213-1254)
Institutions
- Vanderbilt University (US)
- Sejong University (KR)
- Sangji University (KR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-17
- DOI
- https://doi.org/10.3389/fimmu.2024.1457690
- Citations
- 4
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- National Research Foundation
- National Research Foundation of Korea