Adipocyte derived exosomes promote cell invasion and challenge paclitaxel efficacy in ovarian cancer
These observations highlight the capacity of omental adipocytes to generate a pro-tumorigenic and chemoprotective microenvironment in ovarian cancer and other adipose-related malignancies.
Authors
- R. Steven Conlan (ORCID: https://orcid.org/0000-0002-2562-3461)
- Kadie Edwards (ORCID: https://orcid.org/0000-0002-1359-0359)
- Jetzabel García-Parra (ORCID: https://orcid.org/0000-0002-4235-4427)
- Francesca Taraballi (ORCID: https://orcid.org/0000-0002-4959-1169)
- Claire Donnelly
- Deyarina González (ORCID: https://orcid.org/0000-0002-1838-6752)
- Lavinia Margarit (ORCID: https://orcid.org/0000-0002-1989-6949)
- Sadie Jones (ORCID: https://orcid.org/0000-0002-4869-1854)
- Fereshteh Izadi
- Lewis W. Francis (ORCID: https://orcid.org/0000-0002-7803-7714)
- David Howard (ORCID: https://orcid.org/0000-0002-3928-0914)
- Michael Ellis Williams
- Kerryn Lutchman-Sigh
- M. Pugh
Institutions
- Swansea Bay University Health Board (GB)
- Houston Methodist (US)
- Cardiff and Vale University Health Board (GB)
- Cwm Taf University Health Board (GB)
- Swansea University (GB)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1186/s12964-024-01806-4
- Citations
- 20
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.74
Funders
- Health and Care Research Wales
- Swansea University
- Medical Research Council
- European Regional Development Fund