Dexamethasone, Remdesivir and Azithromycin modulate ACE2 and IL-6 in Lung Epithelial Cells
DEX can increase ACE2 expression in vitro and thereby the portal of entry of SARS-CoV-2 into lung cells during an LPS induced inflammation. Simultaneously the inflammatory marker IL-6 is reduced. Comparative database analyses indicate that these processes can also take place in vivo.
Authors
- Carmen Pizarro
- G Ulrich‐Merzenich (ORCID: https://orcid.org/0000-0002-3048-6465)
- A Shcherbakova (ORCID: https://orcid.org/0000-0001-7720-8481)
- Dirk Skowasch
Institutions
- University Hospital Bonn (DE)
Publication Details
- Journal
- Pneumologie
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1055/a-2372-3632
- Citations
- 1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.42