HSV-1 immune escapes in microglia by down-regulating GM130 to inhibit TLR3-mediated innate immune responses
In microglia, one mechanism of HSV-1 immune escape is disruption of the GM130/TLR3 pathway. Berberine protects the GA and enhances TLR3-mediated antiviral immune responses.
Authors
- Wei Lu (ORCID: https://orcid.org/0000-0001-7376-5029)
- Junxian Liu (ORCID: https://orcid.org/0000-0002-5873-0095)
- Xiqian Chen (ORCID: https://orcid.org/0000-0001-6953-4957)
- Hainan Zhang (ORCID: https://orcid.org/0000-0002-1058-0462)
- Jia Liu (ORCID: https://orcid.org/0000-0002-2366-3347)
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1186/s12985-024-02492-x
- Citations
- 5
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 1.20