Patient-reported outcomes during first-line palliative systemic therapy alternated with pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: a single-arm phase II trial (CRC-PIPAC-II)
Patients undergoing BT for unresectable CPM had significant, but reversible alterations in several PROs. Most affected PROs concerned improvements and only two PROs showed deteriorations. Both deteriorated PROs returned to baseline after trial treatment and were of a temporary nature. These outcomes help to design future studies on the role of ePIPAC in the palliative setting.
Authors
- Robin J. Lurvink (ORCID: https://orcid.org/0000-0002-2692-0994)
- Jacobus W. A. Burger (ORCID: https://orcid.org/0000-0003-1988-0186)
- Marinus J. Wiezer (ORCID: https://orcid.org/0000-0001-8996-396X)
- Onno Kranenburg (ORCID: https://orcid.org/0000-0002-2112-4390)
- Djamila Boerma (ORCID: https://orcid.org/0000-0001-9212-1317)
- Koen P. Rovers (ORCID: https://orcid.org/0000-0001-8174-2134)
- Emma C. E. Wassenaar (ORCID: https://orcid.org/0000-0002-7525-9135)
- Vincent C. J. van de Vlasakker (ORCID: https://orcid.org/0000-0003-2549-4054)
- Paulien Rauwerdink
- Simon Willem Nienhuijs (ORCID: https://orcid.org/0000-0002-0104-9477)
- Maartje Los (ORCID: https://orcid.org/0000-0002-4953-5271)
- Geert‐Jan Creemers
- Ignace H J T de Hingh
Institutions
- Radboud University Nijmegen (NL)
- Catharina Ziekenhuis (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- St. Antonius Ziekenhuis (NL)
- Cancer Genomics Centre (NL)
- Netherlands Comprehensive Cancer Organisation (NL)
Publication Details
- Journal
- Surgical Endoscopy
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1007/s00464-024-11185-z
- Citations
- 5
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 2.86