Serum alpha-synuclein in restless legs syndrome
In our study of 113 RLS participants, serum α-syn levels were decreased in RLS patients compared to healthy controls, and increased in the nine patients who received IV iron treatment in correlation with ferritin. This correlation could suggest a mechanism for reduced dopamine transmission in RLS.
Authors
- William G. Ondo (ORCID: https://orcid.org/0000-0001-6090-4261)
- Vera I. Hashem (ORCID: https://orcid.org/0000-0002-5471-8769)
- Aboud Tahanis (ORCID: https://orcid.org/0009-0007-6775-9686)
Institutions
- Houston Methodist (US)
- Cornell University (US)
Publication Details
- Journal
- SLEEP
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1093/sleep/zsae217
- Citations
- 3
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16