Immuno-virological and Clinical Follow-up of Persons With HIV-2 (PWHIV-2) Receiving Bictegravir/Emtricitabine/Tenofovir Alafenamide Fumarate (BIC/FTC/TAF): A Retrospective Study

This retrospective study evaluated Bictegravir (BIC)/emtricitabine (FTC)/tenofovir alafenamide (TAF) in 24 persons with human immunodeficiency virus type 2 (HIV-2, PWHIV-2), 5 naive and 19 pretreated. After a median follow-up of 37.5 months, all PWHIV-2 had a plasma viral load <40 copies/mL. Median CD4 count increased significantly from 580 to 625 cells/mm3, suggesting the effectiveness of BIC/FTC/TAF to treat HIV-2 infection.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2024-09-16
DOI
https://doi.org/10.1093/cid/ciae447
Primary Topic
Hepatitis C virus research
Type
article
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article

Immuno-virological and Clinical Follow-up of Persons With HIV-2 (PWHIV-2) Receiving Bictegravir/Emtricitabine/Tenofovir Alafenamide Fumarate (BIC/FTC/TAF): A Retrospective Study

Véronique Joly, Sophie Matheron, Valentine Marie Ferré, Jade Ghosn et al.
Clinical Infectious Diseases
Hepatitis C virus research
article

Immuno-virological and Clinical Follow-up of Persons With HIV-2 (PWHIV-2) Receiving Bictegravir/Emtricitabine/Tenofovir Alafenamide Fumarate (BIC/FTC/TAF): A Retrospective Study

Véronique Joly, Sophie Matheron, Valentine Marie Ferré, Jade Ghosn, Quentin Le Hingrat, Diane Descamps, M Digumber, Mélanie Cresta, Charlotte Charpentier, Gilles Peytavin, Florence Damond, Yazdan Yazdanpanah
article en

Abstract

This retrospective study evaluated Bictegravir (BIC)/emtricitabine (FTC)/tenofovir alafenamide (TAF) in 24 persons with human immunodeficiency virus type 2 (HIV-2, PWHIV-2), 5 naive and 19 pretreated. After a median follow-up of 37.5 months, all PWHIV-2 had a plasma viral load <40 copies/mL. Median CD4 count increased significantly from 580 to 625 cells/mm3, suggesting the effectiveness of BIC/FTC/TAF to treat HIV-2 infection.

Clinical Infectious DiseasesVol. 80(3)
Inserm (FR), Délégation Paris 7 (FR), Université Paris Cité (FR), Sorbonne Paris Cité (FR), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Bichat-Claude-Bernard (FR)
Good health and well-being
Openalex Percentile: Top 74%
Hepatitis C virus research
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