Innate immunity gene Nod2 protects mice from orthotopic breast cancer
We conclude that Nod2 protects mice from the 4T1 orthotopic breast tumor, and that tumors in Nod2<sup>-/-</sup> mice are predicted to have increased DNA replication and cell proliferation and decreased lipid metabolism compared with WT mice.
Authors
- Serdar A. Gurses (ORCID: https://orcid.org/0000-0002-8781-4554)
- Dipika Gupta (ORCID: https://orcid.org/0000-0002-1155-3861)
- Nivya Varghese
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Indiana University Northwest (US)
- Indiana University School of Medicine
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1007/s11033-024-09927-2
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00