LINC01133 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells by upregulating CTNNB1 by acting as a sponge for miR-214-3p
Our study highlights the role of LINC01133 in positively regulating CTNNB1 expression by inhibiting miR-214-3p, thereby promoting osteogenic differentiation of BMSCs. These findings may provide valuable insights into bone regeneration in osteoporosis.
Authors
- Xiu-Quan Guo
- Ganggang Wang (ORCID: https://orcid.org/0000-0001-5388-0847)
- Zhigang Chen (ORCID: https://orcid.org/0000-0002-4437-4077)
- Chao Tang (ORCID: https://orcid.org/0000-0002-7216-1917)
- Lina Huang
Institutions
- Xi'an Medical University (CN)
- Zoucheng People's Hospital (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Shanghai Eighth People Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1186/s13018-024-05053-8
- Citations
- 3
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.86