Prime-boost immunization with inactivated human adenovirus type 55 combined with an adjuvant enhances neutralizing antibody responses in mice
Prime-boost immunization with the inactivated hAd55 isolate and an AH adjuvant shows promise as a potential approach for preventing hAd55-induced respiratory disease. Further research is needed to evaluate the efficacy and safety of these vaccine candidates in preventing hAd55-associated respiratory illnesses.
Authors
- Sang Hwan Seo (ORCID: https://orcid.org/0000-0002-4518-8858)
- Yunjeong Park
- Soon‐Hwan Kwon (ORCID: https://orcid.org/0000-0002-1582-303X)
- Taesoo Kwon (ORCID: https://orcid.org/0000-0002-9253-2156)
- Jung‐Ah Choi (ORCID: https://orcid.org/0000-0002-0896-4766)
- Dae‐Im Jung
- Manki Song
- Seohee Jung
- Eunji Yang (ORCID: https://orcid.org/0000-0003-2590-4551)
Institutions
- International Vaccine Institute (KR)
- Chungbuk National University (KR)
- Cheongju University (KR)
- Armed Forces Capital Hospital (KR)
Publication Details
- Journal
- Virology Journal
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1186/s12985-024-02491-y
- Citations
- 2
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- Korea Disease Control and Prevention Agency