Air Pollution and Parkinson Disease in a Population-Based Study
In this case-control study of air pollution and PD, higher levels of PM2.5 and NO2 exposure were associated with increased risk of PD; also, higher levels of PM2.5 exposure were associated with increased risk of developing akinetic rigid PD and dyskinesia compared with patients with PD exposed to lower levels. These findings suggest that reducing air pollution may reduce risk of PD, modify the PD phenotype, and reduce risk of dyskinesia.
Authors
- James H. Bower
- Brittany Krzyzanowski (ORCID: https://orcid.org/0000-0002-4774-6120)
- Emanuele Camerucci (ORCID: https://orcid.org/0000-0002-5510-9834)
- Rodolfo Savica (ORCID: https://orcid.org/0000-0002-2543-0627)
- Pierpaolo Turcano (ORCID: https://orcid.org/0000-0002-3240-8348)
- Aidan F. Mullan (ORCID: https://orcid.org/0000-0001-8076-6935)
Institutions
- Barrow Neurological Institute (US)
- Mayo Clinic (US)
- University of Kansas Medical Center (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.33602
- Citations
- 22
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 6.92