Cluster analysis of 100 Marfan patients based on aortic 4D flow MRI and Z-score: insights into disease heterogeneity and stratification of subgroups
Four-dimensional (4D) flow MRI-derived variables of Marfan patients are highly heterogeneous across varying Z-scores. Cluster analysis based on 4D flow MRI and Z-score revealed three distinct subgroups of Marfan patients. A combination of Z-score and 4D flow MRI-derived parameters may identify different stages of aortic disease in Marfan patients.
Authors
- Yskert Von Kodolitsch (ORCID: https://orcid.org/0000-0001-5096-8421)
- Alexander Lenz (ORCID: https://orcid.org/0000-0003-1916-1317)
- Lennart Well (ORCID: https://orcid.org/0000-0003-2491-1346)
- Marion Schuett
- Peter Bannas (ORCID: https://orcid.org/0000-0002-7102-534X)
- Martin Sinn (ORCID: https://orcid.org/0000-0001-9314-4852)
- Felicia Wright (ORCID: https://orcid.org/0000-0001-7338-8542)
- Christoph Riedel (ORCID: https://orcid.org/0000-0001-8342-296X)
- Shuo Zhang (ORCID: https://orcid.org/0000-0002-7427-1933)
- F. Bahr
- Gerhard Adam
- Bjoern P. Schoennagel
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Philips (Germany) (DE)
Publication Details
- Journal
- European Radiology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1007/s00330-024-11034-6
- Citations
- 2
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Deutsche Stiftung für Herzforschung