Resuscitation arterial waveform quantification and outcomes in pediatric bidirectional Glenn and Fontan patients

Hemodynamic waveforms from 2 large prospective observational studies now allow for exploration of physiology during cardiopulmonary resuscitation for unique anatomy associated with single ventricle congenital heart disease. Fewer patients with Fontan physiology (46%) achieved an adequate diastolic blood pressure (defined as ≥ 25 mmHg for neonates and infants and ≥ 30 mmHg for children) than bidirectional Glenn patients during cardiopulmonary resuscitation (91%, p = 0.007). Only 27% of Fontan patients survived to hospital discharge with favorable neurologic outcome after cardiopulmonary resuscitation. Of the bidirectional Glenn patients who survived, 50% developed a new morbidity as quantified by the Functional Status Score.

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Publication Details

Journal
Pediatric Research
Published
2024-09-16
DOI
https://doi.org/10.1038/s41390-024-03564-y
Citations
1
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
Field-Weighted Citation Impact
0.69
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article

Resuscitation arterial waveform quantification and outcomes in pediatric bidirectional Glenn and Fontan patients

Ron Reeder, David A. Hehir, Aisha H. Frazier, Heather A Wolfe et al.
1 citations
Pediatric Research
Cardiac Arrest and Resuscitation
0.69
article

Resuscitation arterial waveform quantification and outcomes in pediatric bidirectional Glenn and Fontan patients

Ron Reeder, David A. Hehir, Aisha H. Frazier, Heather A Wolfe, Vinay Nadkarni, Ryan W. Morgan, John Berger, Maryam Y. Naim, Patrick S. McQuillen, Richard Fernandez, Andrew R. Yates, Kathryn Graham, Robert Berg, Robert M Sutton, Chella A Palmer
article en
1 citations

Abstract

Hemodynamic waveforms from 2 large prospective observational studies now allow for exploration of physiology during cardiopulmonary resuscitation for unique anatomy associated with single ventricle congenital heart disease. Fewer patients with Fontan physiology (46%) achieved an adequate diastolic blood pressure (defined as ≥ 25 mmHg for neonates and infants and ≥ 30 mmHg for children) than bidirectional Glenn patients during cardiopulmonary resuscitation (91%, p = 0.007). Only 27% of Fontan patients survived to hospital discharge with favorable neurologic outcome after cardiopulmonary resuscitation. Of the bidirectional Glenn patients who survived, 50% developed a new morbidity as quantified by the Functional Status Score.

Pediatric ResearchVol. 97(6)
Arkansas Children's Hospital (US), Nationwide Children's Hospital (US), Alfred I. duPont Hospital for Children (US), Children's Hospital of Philadelphia (US), Thomas Jefferson University (US), University of California, Los Angeles (US), Central Michigan University (US), University of Pittsburgh (US), University of California, San Francisco (US), George Washington University (US), Princeton University (US), Washington University in St. Louis (US), University of Utah (US), Children's Hospital Colorado (US), Children's Hospital of Pittsburgh (US), Children's Hospital of Michigan (US), Mattel Children's Hospital (US), UCSF Benioff Children's Hospital (US), The Ohio State University (US), University of Pennsylvania (US), University of Arkansas for Medical Sciences (US), Michigan State University (US), University of Colorado Denver (US), Philadelphia University (US)
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Openalex Percentile: Top 27%
Cardiac Arrest and Resuscitation
0.69
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