Metabolism of primary high-grade serous ovarian carcinoma (HGSOC) cells under limited glutamine or glucose availability
Analysis of the metabolism of primary HGSOC cells rejects the previously proposed hypothesis that there are distinct groups of HGSOC cells with high and low OXPHOS metabolism that respond differently to glutamine or glucose withdrawal and are characterized by ETC protein levels.
Authors
- Daniela Šimčíková (ORCID: https://orcid.org/0000-0002-1227-846X)
- Dominik Gardáš
- Kateřina Hložková
- Michal Hendrych (ORCID: https://orcid.org/0000-0002-1024-7408)
- Petr Heneberg (ORCID: https://orcid.org/0000-0002-0703-951X)
- Martin Hruda (ORCID: https://orcid.org/0000-0002-7606-5164)
- Tiziana Pivetta (ORCID: https://orcid.org/0000-0001-9881-3584)
- Lukáš Rob (ORCID: https://orcid.org/0000-0003-3770-651X)
- Júlia Starková (ORCID: https://orcid.org/0000-0002-2269-5849)
- Petr Vaňhara (ORCID: https://orcid.org/0000-0002-7470-177X)
- Lukáš Moráň (ORCID: https://orcid.org/0000-0002-5534-499X)
- Tomáš Pelikán
Institutions
- University of Cagliari (IT)
- Charles University (CZ)
- Masaryk University (CZ)
- University Hospital in Motol (CZ)
- University Hospital Brno (CZ)
- Masaryk Memorial Cancer Institute (CZ)
- St. Anne's University Hospital Brno (CZ)
- University Hospital Kralovske Vinohrady (CZ)
Publication Details
- Journal
- Cancer & Metabolism
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1186/s40170-024-00355-1
- Citations
- 4
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.14
Funders
- Univerzita Karlova v Praze
- Agentura Pro Zdravotnický Výzkum České Republiky