Blood-based HYAL2 methylation as a potential marker for the preclinical detection of coronary heart disease and stroke
This study presents a strong association of altered HYAL2 methylation in peripheral blood with preclinical CHD and stroke, providing a novel biomarker for risk assessment and early detection of cardiovascular diseases.
Authors
- Haifeng Xu (ORCID: https://orcid.org/0000-0002-6976-1129)
- Lanfei Bi
- Fan Yao (ORCID: https://orcid.org/0000-0002-4393-7296)
- Chong Shen (ORCID: https://orcid.org/0000-0001-6447-6591)
- Mengxia Li (ORCID: https://orcid.org/0000-0003-4443-740X)
- Rongxi Yang (ORCID: https://orcid.org/0000-0002-6655-1986)
- Jialie Jin
- Changying Chen (ORCID: https://orcid.org/0000-0003-0139-6396)
- Yu Liu
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-09-16
- DOI
- https://doi.org/10.1186/s13148-024-01742-7
- Citations
- 3
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China
- Nanjing Medical University