Association of smoking with neurocognition, inflammatory and myeloid cell activation profiles in people with HIV on antiretroviral therapy
sCD14, a marker of monocyte activation, is elevated in PWH who smoke. Although neurocognitive measures and other inflammatory markers did not generally differ, these data implicate smoking-related myeloid activation and monocyte gene dysregulation in the HIV/smoking synergy driving HIV-associated comorbidities.
Authors
- Andrew V. Kossenkov (ORCID: https://orcid.org/0000-0002-1536-0418)
- Mary E. Putt (ORCID: https://orcid.org/0000-0001-7954-1288)
- Anjana Yadav (ORCID: https://orcid.org/0000-0003-0818-963X)
- Toshitha Kannan (ORCID: https://orcid.org/0009-0007-7775-6585)
- Ronald G. Collman (ORCID: https://orcid.org/0000-0002-0508-3701)
- Rebecca L. Ashare (ORCID: https://orcid.org/0000-0003-4664-009X)
- Gabrielle Gionet
- Alisa J. Stephens Shields
- Antoneta Karaj
Institutions
- The Wistar Institute (US)
- University at Buffalo, State University of New York (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- AIDS
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1097/qad.0000000000004015
- Citations
- 3
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.07
Funders
- National Institutes of Health