Ethoxyquin mediates lung fibrosis and cellular immunity in BLM-CIA mice by inhibiting HSP90
This study revealed that EQ regulated pulmonary fibrosis and cellular immunity by inhibiting HSP90, appearing to act through the TGF-β/Smad2/3 pathway. These findings suggest that EQ holds potential as a therapeutic agent for treating RA-ILD.
Authors
- Jie-Rou Huang
- Chaoqian Li (ORCID: https://orcid.org/0000-0002-0916-3661)
- Liang Chen
Institutions
- Hunan Normal University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Hunan Provincial People's Hospital (CN)
Publication Details
- Journal
- Advances in Clinical and Experimental Medicine
- Published
- 2024-09-16
- DOI
- https://doi.org/10.17219/acem/186365
- Citations
- 5
- Primary Topic
- thermodynamics and calorimetric analyses
- Type
- article
- Field-Weighted Citation Impact
- 2.22
Funders
- Natural Science Foundation of Guangxi Province