O03 THE SEVERITY OF COGNITIVE IMPAIRMENT IN PATIENTS WITH ESSENTIAL HYPERTENSION AND VARIOUS FORMS OF ATRIAL FIBRILLATION

Objective: comparative analysis of the severity of cognitive impairment in hypertensive patients with various forms of atrial fibrillation (AF). Materials and methods: During the observation period, 156 patients of both sexes with I–III degree of arterial hypertension (AH) were examined. The average age of patients was 63.8±9.07 years, duration of hypertension was 12.8±7.8 years. To analyze cognitive impairment in patients with AF 3 groups of patients were formed: Group I - hypertension and AF with a permanent form, n = 91, Group II - hypertension and AF with a paroxysmal form, n = 18, Group III - AH and persistent AF form, n=47. Cognitive functions were assessed using the Mini-Cog test, MOCA. The Hospital Anxiety and Depression Scale (HADS) was used to assess anxiety and depression levels. The results are presented as M±SD. Results: The analysis of psychological testing data showed that cognitive impairment is more pronounced in the group of patients with a permanent form of AF. Thus, the total score on the Mini-Cog test in group I of patients was 3.73±1.3 points, while in group II it was 4.0±1.11 points (p<0.05). According to MoCa scale, the total score was superior in group II patients, amounting to 19.7±6.14, while in group I this figure was 19.2±6.08 (p<0.05), and in group III is 18.8±7.22, which indicates a greater severity of cognitive impairment in patients with hypertension and AF with a permanent form and a persistent form. Cognitive functions such as memory are significantly better in group II compared to group I: 7.88±1.99 points versus 6.9±1.78 points, respectively (p>0.05), and decision-making function is significantly better in group III group. It should be noted that according to the HADS scale, the severity of anxiety and depression is higher in group III. Conclusion: A comparative analysis of psychological testing data taking into account the form of AF showed that cognitive impairment is more pronounced in patients with a permanent form of AF.