Synthesis of the Complex Compounds of Zn (II) and Co (II) with Isoniazid (Pyridine-4-Carbohydrazide)

In this paper, the optimal conditions for the complexation of isoniazid (pyridine-4-carbohydrazide) with some 3d-metal Zn (NO3)2 and Co (NO3)2 salts were studied. In this case, complex compounds [Zn(L)2] and [Co(L)2] were synthesized in a 2:1 ratio of Ligand and Metal and a weakly acidic pH=5 environment. The composition and structure of the synthesized complex were studied using modern physico-chemical methods. In particular, the structure of the obtained compound was studied using IR-Fourier spectroscopy, mass spectrometry and elemental analysis methods, and the chemical structure of complex compounds was determined. According to the results of TGA and DTA analysis, it was confirmed that the synthesized complex compounds containing [Me(L)2] are stable and specific to the ligand.