Millmerranones G, a meroterpene isolated from a mangrove-derived fungus <i>Aspergillus</i> sp. GXIMD 03004

One new meroterpene derivative, millmerranones G (<b>1</b>), and three known analogues (<b>2</b>-<b>4</b>) were identified from the mangrove-derived fungus <i>Aspergillus</i> sp. GXIMD 03004, which was isolated from the leaves of mangrove <i>Acanthus ilicifolius</i> L. collected from Beibu Gulf in China. The structure of <b>1</b> was characterised by a comprehensive interpretation of the NMR spectroscopic and HRESIMS data. The absolute configuration for <b>1</b> was established using experimental and calculated ECD data. The anti-<i>Vibrio</i> activities of all compounds were evaluated, the result showed that compounds <b>1</b> and <b>2</b> has weak activity against <i>Vibrio harveyi</i>.