Full-Length Immune Repertoire Reconstruction and Profiling at the Transcriptome Level Using Long-Read Sequencing
FLIRseq enables unbiased and comprehensive analyses of direct V(D)J recombination and immunoglobulin classes, thereby contributing to characterizing pathogenic mechanisms, monitoring minimal residual disease, and customizing adoptive cell therapy.
Authors
- Lihui Zou (ORCID: https://orcid.org/0000-0002-6681-407X)
- Fei Xiao (ORCID: https://orcid.org/0000-0003-2054-901X)
- Xuanmei Luo
- Haozhen Lv (ORCID: https://orcid.org/0000-0001-9109-7669)
- Gaoyuan Sun
- Hongyuan Cui (ORCID: https://orcid.org/0000-0003-4930-1608)
- Jie Ma (ORCID: https://orcid.org/0000-0002-9412-0438)
- Ming Liu (ORCID: https://orcid.org/0000-0002-8662-3190)
- Yifei Li (ORCID: https://orcid.org/0000-0002-3096-4287)
- Chang Li (ORCID: https://orcid.org/0000-0001-9588-8118)
- Chunli Zhang (ORCID: https://orcid.org/0000-0003-2431-607X)
- Yu Fu (ORCID: https://orcid.org/0000-0001-5009-1754)
- Dali Cai
- Lili Zhang (ORCID: https://orcid.org/0009-0005-7341-1438)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Geriatric Hospital (CN)
- First Hospital of China Medical University (CN)
- National Center for Clinical Laboratories (CN)
- China Medical University (CN)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2024-09-17
- DOI
- https://doi.org/10.1093/clinchem/hvae138
- Citations
- 3
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.72